Aberdeen will have three home games, against Hibernian, Kilmarnock and second place rivals Rangers.
The away games are against champions-elect Celtic and Hearts.
Setanta has announced that the Reds will be on live TV at least twice after the split, when they play the Edinburgh clubs.
The Irish broadcaster has not named the game they will show on the final day, but it is highly likely to be the showdown with Rangers at Pittodrie.
If results go the right way, the Dons will be going toe-to-toe with the Gers to decide the SPL's second Champions league place.
Full Top Six fixtures:
Saturday, April 21
Aberdeen v Hibernian 12.30pm - Live on Setanta
Rangers v Hearts 3pm
Sunday, April 22
Kilmarnock v Celtic 2pm - Live on Setanta
Saturday, April 28
Aberdeen v Kilmarnock 3pm
Hibernian v Rangers 3pm
Sunday, April 29
Celtic v Hearts 2pm - Live on Setanta
Saturday, May 5
Rangers v Celtic 12.30pm - Live on Setanta
Hibernian v Kilmarnock 3pm
Sunday, May 6
Hearts v Aberdeen 2pm - Live on Setanta
Saturday, May 12
Hearts v Hibernian 12.30pm - Live on Setanta
Celtic v Aberdeen 3pm
Sunday, May 13
Rangers v Kilmarnock 2pm - Live on Setanta
Sunday, May 20
Aberdeen v Rangers 2pm
Hibernian v Celtic 2pm
Kilmarnock v Hearts 2pm